Human Enhancement

2,634 questions on Human Enhancement, part of Future & Emerging Topics. Below are 12 of them in full, each answered in plain language.

Questions & explanations

1. Give an example of how intermittent fasting might improve cognitive function.

Intermittent fasting involves alternating periods of eating and not eating, for example, eating only during an 8-hour window each day. This may improve cognitive function by triggering cellular repair processes and reducing oxidative stress, which is damage from harmful molecules. Fasting also increases the production of a protein called brain-derived neurotrophic factor (BDNF), which supports the growth of new neurons and strengthens connections between them. Some animal studies show that intermittent fasting improves memory and learning. In humans, the effects are less clear, but some people report better focus and mental clarity during fasting periods. However, the evidence is not strong enough to recommend fasting specifically for cognitive enhancement.

2. Compare the ketogenic diet and intermittent fasting for their effects on brain energy.

Both the ketogenic diet and intermittent fasting can shift the brain's fuel from glucose to ketones, but they do so in different ways. The ketogenic diet achieves this by severely restricting carbohydrates, so the body constantly produces ketones. Intermittent fasting produces ketones only during the fasting periods, and the brain switches back to glucose when you eat. The ketogenic diet leads to a sustained state of ketosis, while intermittent fasting causes periodic ketosis. Both may provide the brain with a more stable energy source and reduce inflammation. However, the ketogenic diet is harder to maintain long-term and may have side effects like nutrient deficiencies. Intermittent fasting is more flexible and may be easier to follow.

3. What safety risks should someone consider before using a home tDCS device?

Using a home tDCS device carries several safety risks. First, incorrect electrode placement can stimulate the wrong brain areas, potentially causing unwanted side effects like mood changes or discomfort. Second, using too high a current or for too long can cause skin burns or lesions under the electrodes. Third, people with certain medical conditions, such as epilepsy or metal implants in the head, should not use tDCS because it could trigger seizures or interfere with devices. Fourth, the long-term effects of repeated tDCS are unknown, especially in young people. Finally, many home devices are not regulated, so the actual current output may differ from what is advertised. It is safer to only use tDCS under professional supervision.

4. A friend says they feel sharper when they skip breakfast. Is there evidence that intermittent fasting boosts cognition?

Some people report feeling more focused and energetic when they skip breakfast, but the scientific evidence for intermittent fasting boosting cognition is mixed. A few studies have found that fasting can improve alertness and reaction time in the short term, possibly due to increased adrenaline or ketone production. However, other studies show no effect or even a decline in performance on complex tasks. The feeling of sharpness might also be because you are not digesting food, which can make you feel sluggish. It is important to note that individual responses vary, and what works for one person may not work for another. Overall, the evidence is not strong enough to recommend intermittent fasting solely for cognitive enhancement.

5. Compare neurofeedback with meditation: which is more effective for reducing stress?

Both neurofeedback and meditation can reduce stress, but they work differently. Meditation involves training your mind to focus and be aware of the present moment, often by paying attention to your breath or a mantra. It is a mental practice you can do anywhere. Neurofeedback uses technology to give you real-time information about your brain waves, helping you learn to produce calm brain patterns. Some studies suggest that meditation has stronger and more consistent evidence for reducing stress, and it is free and easy to learn. Neurofeedback may be helpful for people who have trouble meditating, but it requires expensive equipment and trained professionals. Overall, meditation is more accessible and has more research support.

6. Compare cognitive training programs (like brain games) with physical exercise for preventing cognitive decline.

Physical exercise has stronger evidence for preventing cognitive decline than cognitive training programs like brain games. Exercise improves overall brain health by boosting blood flow, reducing inflammation, and promoting the growth of new brain cells. In contrast, brain games often only improve performance on the specific game itself, with little transfer to real-world cognitive abilities. Many studies have found that brain games do not prevent dementia or slow cognitive decline. Physical exercise, on the other hand, has been consistently linked to better cognitive function in older adults. Combining exercise with other healthy habits like a balanced diet and social engagement is likely the most effective approach.

7. Compare tDCS with caffeine: which is more effective for improving alertness?

Caffeine is generally more effective and reliable for improving alertness than tDCS. Caffeine works by blocking adenosine, a chemical that makes you feel sleepy, and it is absorbed quickly into the bloodstream. A cup of coffee can make you feel more awake within minutes, and the effect lasts for several hours. tDCS, on the other hand, requires special equipment and proper placement, and its effects on alertness are less consistent. Some studies show that tDCS over certain brain areas can increase alertness, but the effect is small and not as strong as caffeine. Also, caffeine is easy to get and has a long history of safe use, while tDCS devices are not approved for cognitive enhancement and may cause skin irritation.

8. Explain the difference between anodal and cathodal tDCS and their typical effects.

In anodal tDCS, the positive electrode (anode) is placed over the target brain area, and this usually increases the excitability of neurons, making them more likely to fire. This is often used to enhance functions like learning or memory. In cathodal tDCS, the negative electrode (cathode) is placed over the target area, which typically decreases neuronal excitability, making neurons less likely to fire. This is sometimes used to reduce overactivity in certain brain regions, for example, to calm down an area that is too active in some disorders. The opposite electrode is placed elsewhere on the body to complete the circuit. The effects are relative and depend on the specific brain region and the task being performed.

9. A 70-year-old wants to keep their mind sharp. What three evidence-based recommendations would you give?

First, I would recommend regular physical exercise, like walking for 30 minutes most days, because it improves blood flow to the brain and supports new brain cell growth. Second, I would suggest staying mentally active by learning something new, such as a language or a musical instrument, or doing puzzles that challenge you. Third, I would emphasize the importance of social connections: spending time with family and friends, joining a group, or volunteering. These activities keep the brain engaged and reduce stress. Additionally, eating a healthy diet like the Mediterranean diet, getting enough sleep, and managing health conditions like high blood pressure are also important. Consistency in these habits is key.

10. Compare the 'playing God' objection to transhumanism with the same objection to vaccination. Are they similar?

The 'playing God' objection to transhumanism is similar to the same objection once raised against vaccination. Critics of vaccination said that preventing disease interfered with divine will or natural selection. Today, most people accept vaccination as moral because it saves lives. Similarly, transhumanists argue that using technology to enhance humans is just another way to reduce suffering. Both objections rely on the idea that nature or God's plan should not be tampered with. However, the scale of transhumanist changes (like radical life extension) is much larger, which makes the objection feel stronger to some. Ultimately, the comparison shows that what seems 'playing God' can become accepted over time.

11. What role does social engagement play in maintaining cognitive health in older age?

Social engagement is very important for maintaining cognitive health in older age. Interacting with others keeps the brain active and challenged, as conversations require attention, memory, and quick thinking. Social activities also reduce stress and lower the risk of depression, which can harm cognitive function. Studies show that older adults with strong social networks have a slower rate of cognitive decline and a lower risk of dementia. Even simple activities like talking on the phone, joining a club, or volunteering can help. Social engagement may also encourage other healthy behaviors like exercise and better diet. Staying connected with family and friends is a key part of a brain-healthy lifestyle.

12. What is the main goal of transhumanism?

Transhumanism is a movement that wants to use technology to improve human abilities, like making people smarter, stronger, or live longer. It believes we can go beyond our natural limits with tools like brain implants or genetic changes. The goal is to create a better human, but still human. Posthumanism goes further and imagines a future where humans evolve into something completely different, maybe not even biological. Augmented humanity is a more practical idea: using tech to help people now, like a hearing aid or a smartwatch, without changing what it means to be human. So transhumanism is about enhancing humans, posthumanism is about becoming posthuman, and augmented humanity is about everyday help.

More Future & Emerging Topics topics

This page shows 12 of 2,634 questions on this topic. The full set, with progress tracking and five agent perspectives per question, is in the JupiteX app — browse the exam catalogue or browse the Learn library.